Lamba Lab
Photoreceptor axons from GFP+ human photoreceptors
Stem Cell-Derived Retinal Organoid
Human cGMP iPSC Photoreceptors integrated into rodent retina
Immune modulation by MANF promotes retinal regeneration
Long-term Vision Restoration with Stem Cell Therapy

Deepak Lamba's Lab @ UCSF Ophthalmology

Dr. Lamba is an Associate Professor in the Department of Anatomy and Ophthalmology at UCSF. He completed his medical training (M.B.B.S.) at the University of Mumbai followed by a Masters in Science (M.S.) in Bioengineering at the University of Illinois, Chicago. He got his Ph.D. at the University of Washington in Neurobiology and Behavior. He started his lab at the Buck Institute for Research in Ageing as an Assistant Professor. He was then recruited as an Associate Professor in 2018 to UCSF.

Dr. Lamba's lab focuses on retinal repair and disease modeling using human stem cell technologies. We have developed in vitro methodologies for generating 3D retinal organoids containing various retinal cell types from human pluripotent stem cells. We are located at the UCSF's Broad Center for Regenerative Medicine and Stem Cell Research.  The goal of the lab is to identify novel retinal therapies using stem cell-based technologies and bringing them closer to the clinic. Towards this goal, the lab works closely with clinicians in the Dept. of Ophthalmology.

The key research interests include (1) exploring the potential and challenges in retinal cell replacement therapies esp. the role of the tissue microenvironment and (2) developing stem-cell based model systems to understand various human retinal degenerations and identifying new therapeutic avenues including genome editing technologies like CRISPR.

We are always looking for talented post-doc candidates. Feel free to reach out.

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