Bachu VS, Kandoi S, Park KU, Kaufman ML, Schwanke M, Lamba DA, Brzezinski JA 4th. An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas. Dev Biol. 2022 Aug;488:131-150. doi: 10.1016/j.ydbio.2022.05.012. Epub 2022 May 26. PubMed PMID: 35644251; NIHMSID:NIHMS1812788.

Chirco KR, Chew S, Moore AT, Duncan JL, Lamba DA. Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model. Stem Cell Reports. 2021 Nov 9;16(11):2690-2702. doi: 10.1016/j.stemcr.2021.09.007. Epub 2021 Oct 14. PubMed PMID: 34653402; PubMed Central PMCID: PMC8580887.

 

Kramer J, Neves J, Koniikusic M, Jasper H, Lamba DA. Dpp/TGFβ-superfamily play a dual conserved role in mediating the damage response in the retina. PLoS One. 2021;16(10):e0258872. doi: 10.1371/journal.pone.0258872. eCollection 2021. PubMed PMID: 34699550; PubMed Central PMCID: PMC8547621.

 

Neves J, Chirco KR, Cedron-Craft W, Chew S, Zhu J, Jasper H, Lamba DA. MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice. Exp Gerontol. 2020 Feb 28;134:110893. doi: 10.1016/j.exger.2020.110893. [Epub ahead of print] PubMed PMID: 32119994; PubMed Central PMCID: PMC7483617.

 

Meyer JG, Garcia TY, Schilling B, Gibson BW, Lamba DA. Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species. Sci Rep. 2019 Oct 28;9(1):15440. doi: 10.1038/s41598-019-51777-7. PubMed PMID: 31659173; PubMed Central PMCID: PMC6817852.

 

Kaufman ML, Park KU, Goodson NB, Chew S, Bersie S, Jones KL, Lamba DA, Brzezinski JA 4th. Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation. Dev Biol. 2019 Sep 15;453(2):155-167. doi: 10.1016/j.ydbio.2019.05.016. Epub 2019 Jun 1. PubMed PMID: 31163126; NIHMSID:NIHMS1552984.

 

Sousa-Victor P, Neves J, Cedron-Craft W, Ventura PB, Liao CY, Riley RR, Soifer I, van Bruggen N, Kolumam GA, Villeda SA, Lamba DA, Jasper H. MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage. Nat Metab. 2019 Feb;1(2):276-290. doi: 10.1038/s42255-018-0023-6. Epub 2019 Jan 14. PubMed PMID: 31489403; PubMed Central PMCID: PMC6727652.

 

Kramer J, Chirco KR, Lamba DA. Immunological Considerations for Retinal Stem Cell Therapy. Adv Exp Med Biol. 2019;1186:99-119. doi: 10.1007/978-3-030-28471-8_4. Review. PubMed PMID: 31654387.

 

Zhu J, Lamba DA. Small Molecule-Based Retinal Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. Bio Protoc. 2018 Jun 20;8(12). doi: 10.21769/BioProtoc.2882. PubMed PMID: 30009216; PubMed Central PMCID: PMC6039118.

 

Rao MS, Pei Y, Garcia TY, Chew S, Kasai T, Hisai T, Taniguchi H, Takebe T, Lamba DA, Zeng X. Illustrating the potency of current Good Manufacturing Practice-compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols. Cytotherapy. 2018 Jun;20(6):861-872. doi: 10.1016/j.jcyt.2018.03.037. Epub 2018 May 21. PubMed PMID: 29793831.

 

Zhu J, Reynolds J, Garcia T, Cifuentes H, Chew S, Zeng X, Lamba DA. Generation of Transplantable Retinal Photoreceptors from a Current Good Manufacturing Practice-Manufactured Human Induced Pluripotent Stem Cell Line. Stem Cells Transl Med. 2018 Feb;7(2):210-219. doi: 10.1002/sctm.17-0205. Epub 2017 Dec 21. PubMed PMID: 29266841; PubMed Central PMCID: PMC5788871.

 

Chao JR, Lamba DA, Klesert TR, Torre A, Hoshino A, Taylor RJ, Jayabalu A, Engel AL, Khuu TH, Wang RK, Neitz M, Neitz J, Reh TA. Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate. Transl Vis Sci Technol. 2017 May;6(3):4. doi: 10.1167/tvst.6.3.4. eCollection 2017 May. PubMed PMID: 28516002; PubMed Central PMCID: PMC5433804.

 

Zhu J, Cifuentes H, Reynolds J, Lamba DA. Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina. Cell Stem Cell. 2017 Mar 2;20(3):374-384.e5. doi: 10.1016/j.stem.2016.11.019. Epub 2017 Jan 12. PubMed PMID: 28089909.

 

Garcia TY, Lamba DA. CRISPR-based genome engineering in human stem cells . In: Patient-Specific Stem Cells. 1st ed. Lamba DA, editor. Boca Raton, FL: CRC press and Taylor and Francis Group; 2017. Chapter 4.

 

Reynolds J, Lamba DA. Modeling Neuro-Retinal Development and Disease in Stem Cells . In: Patient-Specific Stem Cells. 1st ed. Deepak,A, editor. Boca Raton, FL: CRC press and Taylor and Francis Group; 2017. Chapter 11.

 

Lamba DA. Stem cells for Parkinson’s disease . In: Patient-Specific Stem Cells. 1st ed. Lamba DA, editor. Boca Raton, FL: CRC press and Taylor and Francis Group; 2017. Chapter 5.

 

Gutierrez MA, Davis SS, Rosko A, Nguyen SM, Mitchell KP, Mateen S, Neves J, Garcia TY, Mooney S, Perdew GH, Hubbard TD, Lamba DA, Ramanathan A. A novel AhR ligand, 2AI, protects the retina from environmental stress. Sci Rep. 2016 Jul 1;6:29025. doi: 10.1038/srep29025. PubMed PMID: 27364765; PubMed Central PMCID: PMC4929558.

 

Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, Chew S, Qi Y, Jasper H, Lamba DA. Immune modulation by MANF promotes tissue repair and regenerative success in the retina. Science. 2016 Jul 1;353(6294):aaf3646. doi: 10.1126/science.aaf3646. PubMed PMID: 27365452; PubMed Central PMCID: PMC5270511.

 

Garcia TY, Gutierrez M, Reynolds J, Lamba DA. Modeling the Dynamic AMD-Associated Chronic Oxidative Stress Changes in Human ESC and iPSC-Derived RPE Cells. Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7480-8. doi: 10.1167/iovs.15-17251. PubMed PMID: 26595608.

 

Agrawal P, Reynolds J, Chew S, Lamba DA, Hughes RE. DEPTOR is a stemness factor that regulates pluripotency of embryonic stem cells. J Biol Chem. 2014 Nov 14;289(46):31818-26. doi: 10.1074/jbc.M114.565838. Epub 2014 Sep 25. PubMed PMID: 25258312; PubMed Central PMCID: PMC4231659.

 

Reynolds J, Lamba DA. Human embryonic stem cell applications for retinal degenerations. Exp Eye Res. 2014 Jun;123:151-60. doi: 10.1016/j.exer.2013.07.010. Epub 2013 Jul 20. Review. PubMed PMID: 23880530.

 

Mathieu J, Zhang Z, Nelson A, Lamba DA, Reh TA, Ware C, Ruohola-Baker H. Hypoxia induces re-entry of committed cells into pluripotency. Stem Cells. 2013 Sep;31(9):1737-48. doi: 10.1002/stem.1446. PubMed PMID: 23765801; PubMed Central PMCID: PMC3921075.

 

McUsic AC, Lamba DA, Reh TA. Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds. Biomaterials. 2012 Feb;33(5):1396-405. doi: 10.1016/j.biomaterials.2011.10.083. Epub 2011 Nov 23. PubMed PMID: 22115999; PubMed Central PMCID: PMC3249403.

 

La Torre A, Lamba DA, Jayabalu A, Reh TA. Production and transplantation of retinal cells from human and mouse embryonic stem cells. Methods Mol Biol. 2012;884:229-46. doi: 10.1007/978-1-61779-848-1_16. PubMed PMID: 22688710.

 

Nelson BR, Ueki Y, Reardon S, Karl MO, Georgi S, Hartman BH, Lamba DA, Reh TA. Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate. PLoS One. 2011;6(8):e22817. doi: 10.1371/journal.pone.0022817. Epub 2011 Aug 2. PubMed PMID: 21829655; PubMed Central PMCID: PMC3149061.

 

Lamba DA, Reh TA. Microarray characterization of human embryonic stem cell--derived retinal cultures. Invest Ophthalmol Vis Sci. 2011 Jul 1;52(7):4897-906. doi: 10.1167/iovs.10-6504. PubMed PMID: 21345990; PubMed Central PMCID: PMC3175935.

 

Hayashi T, Lamba DA, Slowik A, Reh TA, Bermingham-McDonogh O. A method for stabilizing RNA for transfection that allows control of expression duration. Dev Dyn. 2010 Jul;239(7):2034-40. doi: 10.1002/dvdy.22344. PubMed PMID: 20549727; PubMed Central PMCID: PMC2933403.

 

Brzezinski JA 4th, Lamba DA, Reh TA. Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development. Development. 2010 Feb;137(4):619-29. doi: 10.1242/dev.043968. PubMed PMID: 20110327; PubMed Central PMCID: PMC2827615.

 

Lamba DA, McUsic A, Hirata RK, Wang PR, Russell D, Reh TA. Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells. PLoS One. 2010 Jan 20;5(1):e8763. doi: 10.1371/journal.pone.0008763. PubMed PMID: 20098701; PubMed Central PMCID: PMC2808350.

 

Reh TA, Lamba D, Gust J. Directing human embryonic stem cells to a retinal fate. Methods Mol Biol. 2010;636:139-53. doi: 10.1007/978-1-60761-691-7_9. PubMed PMID: 20336521.

 

Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, Lamba DA, Dauphin DS, Buckingham B, Askari B, Lim R, Tewari M, Gartler SM, Issa JP, Pavlidis P, Duan Z, Blau CA. Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. Cell Stem Cell. 2009 Apr 3;4(4):359-69. doi: 10.1016/j.stem.2009.03.001. PubMed PMID: 19341625; PubMed Central PMCID: PMC2719860.

 

Lamba DA, Gust J, Reh TA. Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice. Cell Stem Cell. 2009 Jan 9;4(1):73-9. doi: 10.1016/j.stem.2008.10.015. PubMed PMID: 19128794; PubMed Central PMCID: PMC2713676.

 

Lamba DA, Karl MO, Reh TA. Strategies for retinal repair: cell replacement and regeneration. Prog Brain Res. 2009;175:23-31. doi: 10.1016/S0079-6123(09)17502-7. Review. PubMed PMID: 19660646.

 

Lamba DA, Hayes S, Karl MO, Reh T. Baf60c is a component of the neural progenitor-specific BAF complex in developing retina. Dev Dyn. 2008 Oct;237(10):3016-23. doi: 10.1002/dvdy.21697. PubMed PMID: 18816825; PubMed Central PMCID: PMC2707830.

 

Lamba D, Karl M, Reh T. Neural regeneration and cell replacement: a view from the eye. Cell Stem Cell. 2008 Jun 5;2(6):538-49. doi: 10.1016/j.stem.2008.05.002. Review. PubMed PMID: 18522847; PubMed Central PMCID: PMC2692223.

 

Lamba DA, Karl MO, Ware CB, Reh TA. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12769-74. doi: 10.1073/pnas.0601990103. Epub 2006 Aug 14. PubMed PMID: 16908856; PubMed Central PMCID: PMC1568922.